Metabolic disorders research lab focuses on understanding the biochemical processes that go wrong in the body. The lab connects biochemistry with real world health problems, thereby design better diagnostics and treatments

• Disease Mechanisms
• Diagnostic Technology
• Metabolomics

1. Unveiling the microbial and metabolic landscape of infantile colic in Indian infants: a metagenomics and culturomics approach for novel probiotic development and maternal-infant gut microbiome interaction. PI: Dr. Aparna C Rajeev,  Mentor: Dr. Raghu (JCMR), (BioCARe) 2025-28,  Rs53 Lakhs

2. Clinical validation of traditional millet recipes roti/dosa/khichidi in maintaining healthy intestinal microbial flora and preventing lifestyle associated complications. Dr. Priya S (CSIR_NIIST), Dr. Raghu K G, JCMR  Dr. Preethi M Shenoy, Biochemistry Dept, DST 2024-2027, Rs 74.33 Lakhs, Jubilee Share Rs 29 Lakhs

1.      Genu George, Shyni G L, Sreelekshmi Mohan , Billu Abraham, Prakasan Nisha, Rajankutty,K, Ranjith S  and RaghuK.G.(2023) In vitro and in vivo anti-inflammatory and anti-arthritic effect of Tinospora cordifolia via modulation of JAK/STAT pathway. Inflammopharmacology, 31,1009-1025.

 2.      Preetha Rani,M.R.,Raj,P.S.,Nair,A.,Ranjith.S.,Rajankutty,K. and Raghu,K.G.(2022)In vitro and in vivo studies reveal the bebeficial effe ts of chlorogenic acid against ER stress mediated EP-phagy and associated apoptosis in the heart of diabetic rat.Chemico-Biological Interactions,35(5):Article 109755

 3.      Anupama Nair, Preetha Rani M R, Salin Raj P , Rajankutty K , Ranjith S and Raghu K.G. Cinnamic acid is beneficial to diabetic cardiomyopathy via its cardioprotective, anti‐inflammatory, anti‐dyslipidemia and antidiabetic properties.  J Biochem Mol Toxicol,2022 Sept.  DOI: 10.1002/JBT.23215  

 4.     Salin Raj P  Anupama Nair, Preetha Rani M R, Rajankutty K, Ranjith S, and Raghu K G.  Ferulic acid attenuates high glucose-induced MAM alterations via PACS2/IP3R2/FUNDC1/VDAC1 pathway activating proapoptotic proteins and ameliorates cardiomyopathy in diabetic rats. December 2022,International Journal of Cardiology, DOI: 10.1016/j.ijcard.2022.12.003.

5.        Soumya RS, Unni TG, Raghu KG. Impact of COVID-19 on the Cardiovascular System: A Review of Available Reports. Cardiovasc Drugs Ther. 2021 Jun;35(3):411-425. doi: 10.1007/s10557-020-07073-y. Epub 2020 Sep 14. PMID: 32926272; PMCID: PMC7487338.