Dr Saritha Francis

Dr Saritha Francis

Dr Saritha Francis

Scientist B
sarithavincent@jmmc.ac.in

Dr. Saritha Francis is a translational scientist with expertise in clinical chemistry, disease risk prediction, and translational biomedicine, with a strong focus on womens health and metabolic disorders. She earned her PhD in Disease Risk Prediction and Stratification from the University of Calicut. She currently serves as Scientist B at the Jubilee Centre for Medical Research, Jubilee Mission Medical College & Research Institute, Thrissur, where she contributes to multidisciplinary research integrating molecular biology, biostatistics, computational biology, and clinical investigation. Her expertise spans Clinical Chemistry and Laboratory Medicine, disease risk stratification, biostatistics, and in silico approaches including molecular docking, molecular dynamics simulation, drug target identification, structure function analysis, and mutation analysis. During her postdoctoral research at JCMR under the mentorship of Dr. Dileep Vijayan, she conducted gene variant analysis of uterine fibroids using whole-exome sequencing. Dr. Francis has extensive experience in experimental and molecular techniques such as nanoparticle synthesis, PCR, blotting techniques, DNA isolation, tissue culture, microbial culture maintenance, protein purification, chromatography, and phytochemical analysis, complemented by proficiency in SPSS, MedCalc, and Minitab. Her current research focuses on developing translational therapeutic strategies for endocrine metabolic disease management, bridging computational discoveries with clinical application, with a long-term vision toward personalized medicine.

  • Endocrine - Metabolic Disease Biology
  • Mechanogenomics
  • Computer Aided Drug Discovery
  • PhD (2010-2018): Clinical Biochemistry and Predictive Disease Risk, University of Calicut, Kerala, India.
  • M.Sc. Biotechnology (2003-2005), Kannur University, Kerala, India.

  • Scientist B, Jubilee Centre for Medical Research- Dec 2024-Present
  • Postdoctoral Fellow, Jubilee Centre for Medical Research-Jan 2022-Dec 2024
  • Assistant Professor, St. Mary's College, Thrissur. Jun 2018-Jan 2022
  • Best Poster Presentation Award, 37th Kerala Science Congress, Kerala Agricultural College, Thrissur (07-10 February 2025)
  • Elite-Silver Award for Fundamentals in Health Research, ICMR (2025)
  • Elite-Silver Award for Cell Culture Technologies, IIT Kanpur (2019)
  • Qualified GATE Examination in Life Sciences (2010)
  • CSIR-JRF, NET Qualified (2009)
  • Award for Excellence in Studies: University Rank in M.Sc. Biotechnology, Kannur University (2006)

1)    1. Area: Ayurbiology

Role: Research Associate
Funding Agency: Institutional Funding (2022–2025)
Project Title: Study on the phenotypic–genotypic relationships of Ayurvedic Prakriti through a multidisciplinary approach
Budget: INR 1,500,000

2. Area: Reproductive Biology
Role: Research Associate
Funding Agency: Department of Health Research (DHR), Government of India (2021–2024)
Project Title: Non-invasive treatment of uterine fibroids through rationally designed selective progesterone receptor modulators
Budget: INR 9,244,910

3. Area: Endocrine and Metabolic Diseases
Role: Investigator
Funding Agency: Council of Scientific and Industrial Research (CSIR), Government of India (2010-2015)
Project Title: Defining criteria for reference interval calculation of selected clinical biochemistry analytes for identification of disease predisposition and risk estimation
Budget: INR 1,400,000

2026

Saritha F, Aswath Kumar R, Dileep KV. Unravelling the structural impact of progesterone receptor mutations in myoma and progesterone intolerance through computational modeling. Computers in Biology and Medicine. 2026;202:111476.

2023

Balaram N, Jose J, Gafoor A, Balachandran S, Saritha F, Dileep KV, Balan S. Acetazolamide responsive early-onset absence epilepsy and ataxia in a toddler with a KCNA2 genetic variant: a case report. Seizure: European Journal of Epilepsy. 2023;110:157-159.

Saritha F, Aiswarya N, Aswath Kumar R, Dileep KV. Structural analysis and ensemble docking revealed the binding modes of selected progesterone receptor modulators. Journal of Biomolecular Structure and Dynamics. 2023;41(21):12401-12410.

2019

Francis S, Mathew J. Decreased expression of cyclooxygenase-2 by the combination of diallyl sulfide and curcumin in HEK 293T cell lines. International Journal of Research. 2019;8(6):1385-1402.

2017

Francis S, Sindu PC, Nesheera KK, Jacob J. Fasting insulin is better partitioned according to family history of type 2 diabetes mellitus than post-glucose load insulin of oral glucose tolerance test in young adults. Journal of Clinical and Diagnostic Research. 2017;1-4.

Francis S, Sindu PC, Nesheera KK, Jacob J. Fasting C-peptide correlated with fasting insulin and post-glucose load C-peptides in young adults, but C-peptides could not be partitioned into groups with and without family history of type 2 diabetes mellitus. International Journal of Contemporary Medical Research. 2017;4:467-472.

2011

Francis S, Jacob J. Insulin resistance. Millennium Zoology. 2011;12(1):48-51.

Francis S, Jacob J. Nanotechnology in medicine. Scientia. 2011;7(1):41-49.